Posts Tagged ‘vitamins diabetes’

Stopping Diabetes Damage With Vitamin C

Friday, March 28th, 2014

Vitamins for Diabetes

Neither vitamin C or insulin prevents damage caused by diabetes, but the combination of the two does.

Please read this informative article from Science Daily, a great resource for the latest and greatest in vitamins and supplements research. We hope that you find it as helpful as we have!

Researchers at the Harold Hamm Oklahoma Diabetes Center have found a way to stop the damage caused by Type 1 diabetes with the combination of insulin and a common vitamin found in most medicine cabinets.

Substituting Vitamins and Supplements for Pharmaceuticals in Type 2 Diabetes

Monday, June 4th, 2012

Here at Wholesale Nutrition, we highly value valid research related to vitamins and supplements. We are continually impressed with the reports from Orthomolecular Medicine News Service and would like to share some of their content with you from time to time. We hope you find it as fascinating as we do!

Commentary by Stuart Lindsey, PharmD
(OMNS May 28, 2012) Just when you thought it was safe to go back into the drugstore, we are going to question authority yet again. Readers may remember Dr. Stuart Lindsey as the Frustrated Pharmacist ( He’s back and at it once more, this time presenting an important supplement-based approach to type 2 diabetes. This essay presents ideas that are very possibly a large part of the solution. As with all OMNS releases, it is not meant to substitute for medical advice. Persons should consult their own doctor before making any health decision. – Andrew W. Saul, Editor

The current treatment of diabetes is among the least successful in medicine, despite billions of dollars spent on research. Many scientists make a career of studying diabetes. Medicine has succeeded in making diabetes very expensive for the patient while making the disease a cash cow for the numerous businesses that cater to the diabetic. We should expect to see some improvement in diabetic treatment, but in fact the basic protocols haven’t changed much in twenty years. Is research getting close to a solution? In my opinion as a practicing pharmacist, the answer is no.

For fifteen years I was the pharmacy manager for an independent neighborhood drug store. I saw the results of many people over the long term as they were introduced to the “sugar-med treadmill.” After prolonged consumption of their diabetic medications, their health did not improve. This was disturbing to me. The long term diabetics all seemed to have the same group of symptoms: they were overweight (due to hyper-insulinemia), edematous (having swelling under the skin), and they all suffered from poor exercise tolerance and had a generally unhealthy appearance. Many of them had peripheral neuropathy (malfunction of nerves), often associated with pain in their hands and feet. Only rarely did they believe their diabetes treatment was actually improving their health.

My interest in the lack of results from standard treatment of diabetes came into sharp focus when pain in my feet led to my being diagnosed with type 2 diabetes. From my observations at work, I already knew that the drug treatments for peripheral neuropathy were questionable. Introducing amitriptyline, gabapentin and Lyrica, which are sedatives and pain killers, made the people sleep a lot. Medically, it’s obvious that sedating nerves doesn’t solve anything. When such patients step up to daily long term narcotics and finally get some pain relief, they still haven’t solved their problems.

Current medical practice relies on the HgbA1c (glycated hemoglobin) level as a measure of blood sugar over several months. The glycated hemoglobin is caused by high levels of sugar binding to hemoglobin inside red blood cells. When it builds up, this means that the body’s biochemicals and organs are being damaged by too much sugar. It was interesting to note how many of the diabetic patients were in the normal range (i.e. HgbA1c < 6.5) but were still in agony over their feet. The problem was that seeing a normal value of HgbA1c, the doctor would hesitate to change the treatment. Apparently, severe foot pain wasn't a symptom that needed attention. I decided to explore the whole HgbA1c issue. The biggest argument you see in diabetes is that diabetes is a 'disposal' issue. A high level of blood sugar is a type of metabolic malfunction that needs to be corrected. Blood sugar has a geography problem. The body seems driven to urinate the sugars out of the body instead of jamming the sugars across supposedly malfunctioning membranes and burning the sugars intracellularly. Medical practice can apply insulin and many types of drugs to insure that the body's tissues metabolize the sugars. Most current diabetic research is targeted at 'breaching the barrier' and making the supposedly malfunctioning membranes more permeable to carbohydrates. When those extra sugar calories are crammed into cells you get advanced glycation end-products (AGE's) that are a threat to the body. In 2005, a UK researcher named Paul Thornalley wrote a paper detailing how many diabetic symptoms are due to a deficiency of thiamine (B-1).[1] Elevated blood sugar promotes a type of toxicity in the kidneys that causes thiamine to be excreted by the kidney at a rate much higher (sixteen to twenty-five times higher) than normal, leading to an acute deficiency of thiamine. From other studies, it is known that deficiencies in all B vitamins, as well as vitamin C and D are common in diabetics.[2] This can cause most of the symptoms of type 2 diabetes, which include: polyneuropathy, nephropathy (kidney damage), retinopathy (eye damage) and eventually heart failure. This raises the question of whether the symptoms are from diabetes or acute beriberi? When I was diagnosed with type II diabetes, I immediately balked at taking the standard diabetic drugs. My doctor wanted to place me on statins, metformin and Byetta, all of which I refused to take. Having researched Dr. Thornalley's theory of diabetes being an acute thiamine deficiency, I started a regimen of vitamin and mineral supplements. Although the pain in my feet was quite severe, I wanted to avoid the regular drug regimen because it relied upon taking lots of pain killers that don't cure the problem. I reasoned that when the body's B vitamin levels are depleted due to high blood sugar, replenishing body stores through diet alone is difficult, so supplementation will be necessary. I started taking a dietary supplement of thiamine (benfotiamine, 250mg 4x/day). I also added of vitamin B-6 (250mg/day) and pyridoxal 5 phosphate (P5P, 100mg/day) magnesium (aspartate, citrate, malate, or chloride) and acetyl-l-carnitine (1000 mg/day) depending on the severity of my peripheral neuropathy symptoms. More recently I've learned of the importance of taking vitamin C to reduce inflammation and prevent oxidation from high blood sugar levels.[2] My doctor did not approve of my self-treatment but was curious. I told him that I was willing to go back to the standard of care if this didn't work. "Positive factors for treating type 2 diabetes are magnesium, exercise, weight control, chromium, dietary fiber, the B-vitamins, vitamin E, vanadium, vitamin C, and complex carbohydrates. I have been using the positive factors for the past 40 years. When patients followed such a program, the results are very good." Abram Hoffer, MD, PhD [3] The most overt of the neuropathy symptoms started to subside rapidly. Within a week, the shooting pains in my ankles were mostly gone. All of the other symptoms of numbness of the toes and overall pain of the feet including the "boot effect" (the feeling that you have your boots or socks on) were mostly gone in three weeks. Now I know this treatment may not be a cure for diabetes. But it is a valid and reasonably inexpensive way to control the symptoms, which are held at bay as long as you keep your thiamine levels high. If you quit taking thiamine and the other B vitamins, the symptoms come roaring back. I looked for the inevitable deterioration of my health that had been predicted. Ignore your blood sugar levels at your peril I was told. I was going to have kidney problems, my pancreas would stop cooperating and my vision would become blurry as the elevated sugars damaged my retinas. But the only sign of an active problem was the neuropathies in my feet which were quite painful at times: numbness of my toe area and shooting pains in my foot joints. I also had the feeling that the circulation of my feet was poor as my feet were always cold. After two years I finally got blood tests. I still felt very good having lost some weight, with no vision problems, and my energy level and psychological attitude were all fine.I was actually afraid to look at the results and finding out that I had finally outsmarted myself and got hurt. There is a quite a propaganda machine built around the treatment of diabetes. As I drove over to retrieve my blood tests I did a mental check of how I felt. I decided I couldn't have a lot wrong with me as I just felt too good. My blood tests were amazingly free of problems related to elevated blood sugar, and I had few other related discernible health defects. This thiamine treatment did not change my HgbA1c (which is currently 9.1, and that is high) or my resting blood sugars (fasting blood sugars still between 180-190, and those also are high). Values like these are supposed to indicate a poor quality of health. My recent blood tests indicated: Creatinine, urine 86.7mg/dl. Scale 20-370; low normal. Microalbumin/Creatinine ratio 9.2mg/GCr. Scale 0-30; low normal. Creatinine and microalbumineria values are the so called "Canary in the Coal Mine" indicators. The kidneys are supposed to go first when Advanced Glycation Endproducts (AGEs) have started your march to health failure because you didn't keep your HgbA1c values within range. I think my two-plus years is long enough for this to play out. I had my eyes checked for sugar damage to my retinas. I have no sugar damage to my eyes whatsoever. I am 61 years old and have 20-25 vision in both eyes. Jonathan Wright, MD, is among those who have noted that skin tags may be connected to diabetes; interestingly enough the skin tags on my arms have all disappeared. However, my health hasn't failed due to hyperglycemia, although it is still a problem. In my case, the unusual positive results are evidently due to my nutritional approach. I substituted supplements of several essential nutrients for pharmaceuticals and stayed in relatively good health. And I continue to try supplementing with other nutrients such as antioxidants which are known to help prevent diabetes. [2] This suggests that the health issues are actually caused by nutritional deficiencies that can be easily prevented. I am hoping this simple (and non-toxic) experiment on myself will lead the field to discussing the validity of substituting vitamins in diabetes treatment. The treatment of diabetes as it now stands is complicated and expensive. I am spending about $130/month on supplements, and during this two year experiment I have not given my doctor a single dime for advice on how to regulate my HgbA1c value. I imagine I've saved more than twice that amount by avoiding paying for drugs and doctor visits. Is this justified? If my health remains good and I have no other serious problems, I believe it is. If all diabetics would supplement with B vitamins and vitamins C, D, and E, and minerals such as calcium and magnesium, they would lessen their problems with insulin and blood sugar, and the other serious symptoms of diabetes.[2] The reason is that most people in our society, especially including diabetics, have deficiencies of these essential nutrients that are known to be related to diabetes. But this essay is also an attempt to unseat some basic tenets of the medical fiasco known as diabetes. The prevalence in 2011 of type II world-wide according to the World Health Organization (WHO) is 346 million, and some 3.4 million people dies in 2004 as a consequence of the disease. The WHO predicts that the deaths attributable to diabetes will double between 2005 and 2030. [4] With this kind of projection a "Manhattan Project" kind of response seems necessary. So what is the intellectual problem that seems so intractable to the medical research community? The standard treatments to lower blood sugar and HgbA1c were recently tested in medical trials. The ACCORD trials were meant to validate once and for all that the closer a patient got to a HgbA1c level of 6% the healthier a person became. Instead there was 22% increase in mortality from heart failure.[5] This unexpected value caused the FDA to terminate the trial midstream. Is it possible that the HgbA1c value should not be a primary goal in evaluating diabetes treatments? If you go to PubMed and enter the keywords "thiamine deficiency" and "diabetes" you will get dozens of references that describe how many symptoms of diabetes are caused by a thiamine deficiency it generates. Deficiencies of B vitamins and other essential nutrients are important in diabetes.[2] This should be required reading for all doctors who treat or research diabetes. Currently in conventional management of diabetes, supplement based nutrition therapy is utterly neglected. The National Diabetes Fact Sheet reported that in 2007, the direct medical costs of diabetes nationally was estimated at $116 billion (USD). [6] Diabetic patients can feel overwhelmed by a diagnosis of hyperglycemia, but are often comforted by the complicated explanations and sudden increase in activity and attention directed at them. The possibility that they are being misled just doesn't come up. Even if patients decide to do their own research it can be confusing. The cause of diabetes is basically unknown, but they are told that with some major alterations to one's lifestyle and lots of drugs liberally applied they can lead a relatively normal life. However for the truly curious, a large block of mainstream nutrition ideas of which the doctors are mostly ignorant can be freely accessed on the internet. When a patient presents this alternative information to the doctor today, they are comforted and told that they are already getting the cutting edge treatment. But even three years after the revelations of the ACCORD trials there has been no major correction of the type II treatment protocols that addresses the unexplained mortality issues revealed by the trials. Even if my vitamin arguments are only partially correct, the implications for mainstream medicine are staggering. These ideas need wide discussion the field, because patients with diabetes need some new ideas. For further reading: Melvyn R. Werbach's Nutritional Influences on Illness contains a valuable review of research indicating the therapeutic value of supplements, and their specific dosages, for diabetics. Third Line Press, 2nd Edition, 1996 ISBN-10: 0961855053; ISBN-13: 978-0961855055. Endocrinologist and Professor of Medicine (University of Kentucky) J. W. Anderson is perhaps the world's leading researcher on fiber and diabetes. As much a book about fiber as it is about overconsumption of sugar, The Saccharine Disease by T. L. Cleave (1975) is available in its entirety for free online at and also at References: 1. Thornalley PJ: The potential role of thiamine (vitamin B-1) in diabetic complications. Curr Diabetes Rev, 2005; 1:287-298 2. Brighthope IE (2012) The Vitamin Cure for Diabetes: Prevent and Treat Diabetes Using Nutrition and Vitamin Supplementation. Basic Health Publications ISBN-13: 978-1591202905. 3. 4. World Health Organization. Diabetes. Retrieved from [ ] 5. Action to Control Cardiovascular Risk in Diabetes Study Group, Gerstein HC, Miller ME, Byington RP, et al: Effects of intensive glucose lowering in type II diabetes. N Engl J Med, 2008; 358: 2545-2559. 6. National Diabetes Fact Sheet, 2011. Retrieve from: (Much of this article is drawn from Lindsey SL Substituting vitamins and supplements for pharmaceuticals in type 2 diabetes J Orthomolecular Med 2012, 27:1; p 5-8. We thank the Journal for permission to reprint it here in edited form .) Nutritional Medicine is Orthomolecular Medicine Orthomolecular medicine uses safe, effective nutritional therapy to fight illness. For more information: Find a Doctor To locate an orthomolecular physician near you: The peer-reviewed Orthomolecular Medicine News Service is a non-profit and non-commercial informational resource. Editorial Review Board: Ian Brighthope, M.D. (Australia) Ralph K. Campbell, M.D. (USA) Carolyn Dean, M.D., N.D. (USA) Damien Downing, M.D. (United Kingdom) Dean Elledge, D.D.S., M.S. (USA) Michael Ellis, M.D. (Australia) Martin P. Gallagher, M.D., D.C. (USA) Michael Gonzalez, D.Sc., Ph.D. (Puerto Rico) William B. Grant, Ph.D. (USA) Steve Hickey, Ph.D. (United Kingdom) James A. Jackson, Ph.D. (USA) Michael Janson, M.D. (USA) Robert E. Jenkins, D.C. (USA) Bo H. Jonsson, M.D., Ph.D. (Sweden) Thomas Levy, M.D., J.D. (USA) Stuart Lindsey, Pharm.D. (USA) Jorge R. Miranda-Massari, Pharm.D. (Puerto Rico) Karin Munsterhjelm-Ahumada, M.D. (Finland) Erik Paterson, M.D. (Canada) W. Todd Penberthy, Ph.D. (USA) Gert E. Schuitemaker, Ph.D. (Netherlands) Robert G. Smith, Ph.D. (USA) Jagan Nathan Vamanan, M.D. (India) Andrew W. Saul, Ph.D. (USA), Editor and contact person. Email: [email protected] Readers may write in with their comments and questions for consideration for publication and as topic suggestions. However, OMNS is unable to respond to individual emails. To Subscribe at no charge:

Part 2: I’m diabetic. Which vitamins should I take?

Monday, March 7th, 2011

In Part 1 of this series we discussed how diabetics should be checked for vitamin B deficiencies to avoid neuropathy, or nerve damage, and help to reduce their sensitivity to blood sugar fluctuations. But, B vitamins are not the only ones that diabetics should be concerned about. Other vitamins and minerals can have a profound effect on insulin requirements and secretion, glucose tolerance, the loss of body fat, and other health concerns with diabetics.

Vitamin D deficiency is very common around the world and diabetics are no exception. Some studies report vitamin D deficiencies in as high as 90% of diabetics. It is unknown whether the deficiencies are caused by the condition, or a lack of sun exposure. Vitamin D is very important for diabetics because it is used in the pancreas to regulate pancreatic beta cells that produce insulin. The deterioration of these cells is the main cause of Type 1 diabetes. Studies have shown that Type 2 diabetics with vitamin D deficiencies have less control over the disease as their deficiency increases. It is very important to have your doctor check your vitamin D levels, even if you supplement with vitamin D. Many people are unable to convert vitamin D to the biologically active forms usable by the body.

Diabetes causes inflammation throughout the body, which increased the body’s requirements for antioxidants. Vitamin C is very effective in reducing the free radical byproducts of inflammation and in turn, helping diabetics to avoid complications such as damage to the nerves, kidneys, and eyes. Vitamin C and E together can help to prevent vascular damage that leads to heart disease, narrowing of capillaries, and hardening of the arteries. Vitamin C also lowers sorbital, the sugar that accumulates in the body.

Vitamin C should be taken with plenty of water while vitamin E must be consumed with fats. Most doctors recommend that diabetics incorporate omega 3 fatty acids into their diets while combining them with vitamin E. The best vitamin C is a buffered vitamin c powder, which is highly absorbable and has very little acid. This form is more easily tolerated as a daily supplement than highly acidic chewables.

When taking antioxidants, diabetics should work with their doctors and monitor their activity levels. As you have probably been told, regular exercise is the easiest way to manage diabetes. The benefits are not only obtained through the loss of body fat. Exercise is predominantly recommended to diabetics because intense activity produces free radicals that activate the body’s immune response. This is essentially an antioxidant reaction that the body produces on its own. Your doctor may recommend that you continue to eat healthy fruits and vegetables if you exercise regularly, but that you not take additional antioxidant vitamins. If you exercise infrequently, your doctor may advise you to only take antioxidant vitamins on days that you do not exercise.

About the Author: Phil Le Breton is owner at Wholesale Nutrition. He has a strong interest in helping people achieve greater brain and body health with vitamins and supplements, with an emphasis on vitamin C powder. Wholesale Nutrition has provided the world with the best vitamin C and wholesale vitamins since 1970. Visit to buy high-quality discount vitamins today!


Diabetes Mellitus-Information
Diabetes Health
Medicine Net

Part 1: I’m diabetic. Which vitamins should I take?

Wednesday, March 2nd, 2011

Diabetes is a serious, life-threatening, chronic medical condition affecting almost 10% of the population in the US. It is currently the third leading cause of death after heart disease and cancer. Diabetes can lead to nerve damage, blindness, kidney failure, atherosclerosis (narrowing of the arteries), stokes, and coronary heart disease. The effects of diabetes on the small vessels of the body lead to the most common causes of death in diabetic individuals.

Controlling blood sugar can help diabetics to prolong their life and the quality of it. However, keeping blood glucose at an acceptable level does not protect diabetics from all of the dangers associated with diabetes. An overwhelming percentage of diabetics not only have elevated blood glucose levels, but also have multiple vitamin deficiencies or higher vitamin requirements than someone without diabetes. Regular blood tests can help you and your physician to identify deficiencies and determine proper dosages of specific vitamins that will help you to improve your health.

One common problem for diabetics is low B vitamin levels, particularly biotin, B1, B6 and B12. Proper levels of the B vitamin folic acid, along with B12 and B6, have been found to help protect nerve cells from the damage caused by diabetes. Neuropathy is nerve damage, usually first seen in the feet of diabetics, that causes pain or numbness that can lead to amputation. Over 60% of diabetics will suffer from the effects of neuropathy. Having your doctor check and monitor your vitamin B levels can help you to avoid neuropathy.

Some people also have trouble converting B vitamins into their active forms. Supplementing with B vitamins and having your doctor monitor you can help you to determine which levels are not increasing or not being converted. If this is the case for you, your doctor can prescribe the metabolically active form of the vitamins that you need. Diabetics should be careful of niacin consumption (vitamin B3) because it can impair glucose tolerance.

B vitamins improve blood flow into the small blood vessels that are so easily damaged in diabetics. This also helps to maintain the responsiveness of nerve cells and avoid nerve damage. A deficiency in the active form of any B vitamin can cause a hypersensitivity to blood sugar changes and impaired glucose tolerance, increasing your chances of suffering the life-threatening effects of diabetes.

Other vitamins and supplements that help to control and minimize the damaging effects of diabetes include vitamin E, vitamin D, and vitamin C. Diabetics are often deficient in many of these, usually because their bodies have an increased demand for these vitamins and nutrients. In Part 2 of this series, “I’m diabetic. Which vitamins should I take?” we will discuss the different roles that these vitamins and supplements play in controlling the effects of diabetes and why your doctor may recommend that you avoid certain vitamins when you exercise. Get the benefits of the best vitamin C (vitamin c powder), vitamin E and vitamin D by working closely with your physician and closely monitoring your condition.

About the Author: Phil Le Breton is owner at Wholesale Nutrition. He has a strong interest in helping people achieve greater brain and body health with vitamins and supplements, with an emphasis on vitamin C powder. Wholesale Nutrition has provided the world with the best vitamin C and wholesale vitamins since 1970. Visit to buy high-quality discount vitamins today!


Diabetes Mellitus-Information
Diabetes Health

Part 2: Controlling Damage by Type 1 Diabetes

Wednesday, July 28th, 2010

The damage caused by type 1 diabetes can lead to disease and death. By stopping, reducing or reversing the damage, patients diagnosed with type 1 diabetes can avoid things like blindness, amputation, kidney disease, and many vascular complications. The vascular damage done, as we discussed in Part 1 of the series “Controlling Damage by Type 1 Diabetes”, is caused largely in part by endothelial dysfunction and can lead to hardening of the arteries, heart attack, stroke, heart disease, and death.

We touched on how vitamin C combined with insulin therapy can help to reverse endothelial dysfunction and improve patient outcomes when treating type 1 diabetes. Many people believe that controlling their symptoms with insulin is all that they can do to combat this disease. However, controlling blood sugar is only one way to look at it.

Scientists have long since been interested in not only controlling blood sugar, but also controlling the damage that is done, even when the blood sugar is being controlled. Endothelial dysfunction is what they believe can be causing the body to be resistant to insulin and furthering the damage to the circulatory system.

What they have found is that the endothelial cells actually remember how they were functioning before blood sugar was controlled and continue to act this way even after glucose levels are regulated. This causes many problems with cholesterol levels, dilation, hardening of the arteries, inflammation, and blood platelet function. So, even when a type 1 diabetic is fully controlling insulin levels, these endothelial cells continue to do damage.

Not only has vitamin C been proven to regulate cholesterol and control inflammation, but it has also been shown to erase this “memory” of the damaging habits of the endothelial cells. By doing this, the cells are allowed to regain their function as they heal. They stop creating the free radicals that lead to oxidative stress and disease. They are better equipped to regulate levels of glucose and insulin inside of the vessels. Supplements of vitamin C can help to break the chain reaction of events that lead to endothelial dysfunction.

Now, it is important to keep in mind that your doctor must be involved in deciding on a vitamins and supplements routine that is right for you and your health. The studies that have been done on vitamin C and endothelial dysfunction were performed with intravenous vitamin C. It can be difficult to achieve the right blood serum concentrations of vitamin C necessary to control damage without doctor supervision. Common oral supplements are often too weak or contain too many additives to achieve the desired results. Some patients have been able to reach the right concentrations without the intestinal disturbances of most oral supplements by using a potent buffered vitamin C powder. Talk with your doctor about supplementing with the best vitamin C and ordering discount vitamins online to make the maintenance of your type 1 diabetes affordable.

About the Author: Phil Le Breton is owner at Wholesale Nutrition. He has a strong interest in helping people achieve greater brain and body health with vitamins and supplements. Wholesale Nutrition has provided the world with discount vitamins and the best vitamin C since 1970. Visit to buy high-quality, low-cost wholesale vitamins today!

Part 1: Controlling Damage by Type 1 Diabetes

Wednesday, July 28th, 2010

Type 1 diabetes is a serious autoimmune disease. It causes the immune system to attack the healthy cells of the pancreas. These cells are responsible for producing insulin, which the body needs to balance blood glucose levels. Type 1 diabetes affects nearly three million Americans today. It usually comes on in childhood and requires constant management.

People diagnosed with type 1 diabetes have to check their insulin levels multiple times a day. Multiple insulin injections per day are normally required. In some cases, an insulin pump that continually provides the blood with insulin is needed. Unfortunately, insulin injections and even insulin pumps do not prevent the damage that type 1 diabetes can cause.

Type 1 diabetics can suffer from blindness, kidney failure, heart attack, stroke, infertility or pregnancy complications, nerve damage, low circulation, and may even end up having multiple amputations because of the damage. The blood sugar and insulin levels of a type 1 diabetic require constant and meticulous observation. It can be nearly impossible to control because so many things can affect blood sugar. Hormones, stress, food, exercise, rest, medications, illness, and age are only some of the factors that can change these levels.

Atherosclerotic vascular disease (ASVD or atherosclerosis) is the leading cause of death in patients diagnosed with type 1 diabetes. It is not fully understood why, but diabetes affects the function of the endothelial cells that line the arteries, blood vessels and capillaries. These cells normally emit nitric oxide, which relaxes the muscles within the blood vessels. They also prevent leukocyte adhesion and regulate the removal of fats and proteins from the blood. They are responsible for communicating how much glucose or insulin is in the blood at any given time. When they are damaged, it is referred to as endothelial dysfunction. Endothelial dysfunction is commonly seen in patients with insulin resistance before diabetes develops.

Endothelial dysfunction is thought to be the trigger for arteries to harden. It causes chronic inflammation and oxidative stress. Endothelial dysfunction can be identified when arteries do not completely dilate when exposed to a trigger. Your doctor can measure dilation with an ultrasound. If there is not enough dilation, it is a sign that the endothelium cells are not producing enough nitric oxide.

Normal functioning endothelial cells should make and react to nitric oxide. Nitric oxide is produced and used by the body to control inflammation and remove free radicals that can lead to oxidative stress and vascular diseases. It is now known that type 1 diabetics can benefit from supplementing with the best vitamin C in addition to controlling blood glucose levels with insulin. Vitamin C has been shown to improve epithelial function and can even help to increase insulin sensitivity. Many doctors recommend antioxidant therapy in conjunction with insulin administration. If you supplement with vitamin C, the endothelial cells can actually regain their full function and prevent deadly complications of type 1 diabetes.

Vitamin C controls inflammation, regulates cholesterol levels, and clears out free radicals that can affect more cells. Studies show that the blood serum levels of vitamin C must be high enough to achieve the desired results. Lower quality vitamin C products may have oxidized contaminates that can do more harm than good, so that is why it is recommended that you use only the best vitamin C products on the market. If you plan on buying discount vitamins, be sure that you are purchasing them from a reputable site that provides high quality vitamins and supplements.

About the Author: Phil Le Breton is owner at Wholesale Nutrition. He has a strong interest in helping people achieve greater brain and body health with vitamins and supplements. Wholesale Nutrition has provided the world with discount vitamins and the best vitamin C since 1970. Visit to buy high-quality, low-cost wholesale vitamins today!

Juvenile Diabetes and Vitamin D

Tuesday, June 30th, 2009

Studies have shown that an overwhelming percentage, around 85%, of adolescents with type 1 diabetes have inadequate levels of vitamin D. Type 1 diabetics are known to usually have less bone density and are considered to be at high risk for bone fractures. We know that adequate levels of vitamin D lead to stronger bones and higher bone density, that’s why we have added vitamin D to fortified milk. What you may not know is that hindered vitamin D absorption and synthesis could have a negative effect on your child’s moods, sleep patterns, stress levels, mental health and cognitive abilities. Are underlying medical conditions, race or body fat percentage preventing your child from converting vitamin D into a usable, active hormone form?

The current FDA recommended daily allowance of vitamin D is 400 units of vitamin D per day for adults, 200 units per day for adolescents. For a healthy adult to get a minimum daily recommended amount, they would need to drink four 8-ounce glasses of milk every day. You can also get vitamin D from the sun. For 400 units, that would be about thirty minutes of peak hour sun, four days per week. But there are many factors that can affect how much vitamin D you actually get and use from these sources.

Relying on the sun or milk for vitamin D may not be feasible. Taking vitamins and supplements is usually necessary. People with hyperparathyroidism, kidney disease or liver disease should not necessarily take vitamin D supplements because of their inability to convert it to an active hormone form, so speak with your endocrinologist if your child has any of these conditions. Furthermore, you should be aware that the darker your skin is and the higher body fat percentage you have, the less vitamin D you will absorb from the sun. Also, if your child eats a diet low in monounsaturated fats or if they have a condition that causes a reduction in fat absorption, they will also have a hindered ability to absorb vitamin D and may need to supplement.

Complications with diabetes are often brought on by stress. Stress levels in general are kept in check by vitamin D. Additionally, blood sugar levels affect mood and cognition. Mood swings and lack of cognition brought on by blood sugar fluctuations can be lessened and even eliminated by maintaining adequate levels of vitamin D in the body in some cases. This is because vitamin D increases the serotonin levels in the brain. Serotonin is the neurotransmitter that controls moods in the brain.

Adequate vitamin D translates into adequate serotonin. Serotonin regulates stress, anger, depression, aggression, appetite, behavior and more. Since stress aggravates and worsens diabetes symptoms and risks, controlling the serotonin levels in a juvenile diabetic, type 1 or type 2, may help reduce health risks. These risks include psychosis as a result of sleep deprivation, depression, long-term high or low blood glucose levels, high blood pressure, heart disease and stroke.

Have your child’s vitamin D levels checked by their doctor. If levels are low or deficient, try to work in food sources of vitamin D, such as shrimp, salmon, cod liver oil and vitamin D fortified milk. You may want to ask your doctor about the use of vitamins and supplements to increase vitamin D levels. Have levels regularly checked to monitor absorption and proper dosage for your child.

About the Author: Phil Le Breton is owner at Wholesale Nutrition. He has a strong interest in helping people achieve greater brain and body health. For more information about C-Salts, otherwise known as the best Vitamin C, or about other Vitamin C powder products, visit where you can buy Vitamins and Supplements of the highest quality.