Posts Tagged ‘anti inflammatory vitamin’

Should RDA of Vitamin C Be Increased?

Monday, August 31st, 2015

vitamin c inflammation

Are you treating your disease, or symptoms of your disease?

Should recommended dietary allowance (RDA) of vitamin C be increased? “An excellent diet with the recommended five to nine daily servings of fruits and raw or steam-cooked vegetables, together with a six-ounce glass of orange juice, could provide 200 milligrams of vitamin C a day. But most Americans and people around the world do not have an excellent diet.” Is 200 mg enough? What if you have an inflammatory condition, such as high blood pressure, diabetes, or heart disease? Does this increase your need for anti-inflammatory vitamin C?

Educate yourself. Are you treating symptoms or underlying causes of disease? Could your medication be contributing to the imbalance in your body that is causing inflammation? Supplementing with vitamin C powder may be just what you need to improve your condition and increase the duration and quality of your life. Check out this article published by News Medical Life Sciences & Medicine.

Healthier Levels of Vitamin C Can Reduce Inflammatory Conditions

The recommended dietary allowance, or RDA, of vitamin C is less than half what it should be, scientists argue in a recent report, because medical experts insist on evaluating this natural, but critical nutrient in the same way they do pharmaceutical drugs and reach faulty conclusions as a result.

The researchers, in Critical Reviews in Food Science and Nutrition, say there’s compelling evidence that the RDA of vitamin C should be raised to 200 milligrams per day for adults, up from its current levels in the United States of 75 milligrams for women and 90 for men.

Rather than just prevent the vitamin C deficiency disease of scurvy, they say, it’s appropriate to seek optimum levels that will saturate cells and tissues, pose no risk, and may have significant effects on public health at almost no expense – about a penny a day if taken as a dietary supplement.

“It’s time to bring some common sense to this issue, look at the totality of the scientific evidence, and go beyond some clinical trials that are inherently flawed,” said Balz Frei, professor and director of the Linus Pauling Institute at Oregon State University, and one of the world’s leading experts on the role of vitamin C in optimum health.

“Significant numbers of people in the U.S. and around the world are deficient in vitamin C, and there’s growing evidence that more of this vitamin could help prevent chronic disease,” Frei said. “The way clinical researchers study micronutrients right now, with the same type of so-called ‘phase three randomized placebo-controlled trials’ used to test pharmaceutical drugs, almost ensures they will find no beneficial effect. We need to get past that.”

Unlike testing the safety or function of a prescription drug, the researchers said, such trials are ill suited to demonstrate the disease prevention capabilities of substances that are already present in the human body and required for normal metabolism. Some benefits of micronutrients in lowering chronic disease risk also show up only after many years or even decades of optimal consumption of vitamin C – a factor often not captured in shorter-term clinical studies.

A wider body of metabolic, pharmacokinetic, laboratory and demographic studies suggests just the opposite, that higher levels of vitamin C could help reduce the chronic diseases that today kill most people in the developed world – heart disease, stroke, cancer, and the underlying issues that lead to them, such as high blood pressure, chronic inflammation, poor immune response and atherosclerosis.

“We believe solid research shows the RDA should be increased,” Frei said. “And the benefit-to-risk ratio is very high. A 200 milligram intake of vitamin C on a daily basis poses absolutely no risk, but there is strong evidence it would provide multiple, substantial health benefits.”

An excellent diet with the recommended five to nine daily servings of fruits and raw or steam-cooked vegetables, together with a six-ounce glass of orange juice, could provide 200 milligrams of vitamin C a day. But most Americans and people around the world do not have an excellent diet.

Even at the current low RDAs, various studies in the U.S. and Canada have found that about a quarter to a third of people are marginally deficient in vitamin C, and up to 20 percent in some populations are severely deficient – including college students, who often have less-than-perfect diets. Smokers and older adults are also at significant risk.

Even marginal deficiency can lead to malaise, fatigue, and lethargy, researchers note. Healthier levels of vitamin C can enhance immune function, reduce inflammatory conditions such as atherosclerosis, and significantly lower blood pressure.

•A recent analysis of 29 human studies concluded that daily supplements of 500 milligrams of vitamin C significantly reduced blood pressure, both systolic and diastolic. High blood pressure is a major risk factor for heart disease and stroke, and directly attributes to an estimated 400,000 deaths annually in the U.S.

•A study in Europe of almost 20,000 men and women found that mortality from cardiovascular disease was 60 percent lower when comparing the blood plasma concentration of vitamin C in the highest 20 percent of people to the lowest 20 percent.

•Another research effort found that men with the lowest serum vitamin C levels had a 62 percent higher risk of cancer-related death after a 12-16 year period, compared to those with the highest vitamin C levels.

Laboratory studies with animals – which may be more accurate than human studies because they can be done in controlled conditions and with animals of identical genetic makeup – can document reasons that could explain all of these findings, Frei said.

Critics have suggested that some of these differences are simply due to better overall diet, not vitamin C levels, but the scientists noted in this report that some health benefits correlate even more strongly to vitamin C plasma levels than fruit and vegetable consumption.


News Medical Life Sciences & Medicine

Critical Reviews in Food Science and Nutrition

About the Author: Stacy A. Pessoney is Wholesale Nutrition’s Chief Editor and Communications Research Director. She has a strong interest in helping people achieve greater brain and body health with the help of vitamins and supplements, with an emphasis on vitamin C powder in the form of buffered vitamin C. Wholesale Nutrition has provided the world with the best vitamin C and wholesale vitamins since 1970. Visit to buy high-quality discount vitamins today!

Is Low Immunity Making you Fat?

Saturday, November 12th, 2011

The stress hormone cortisol is made from cholesterol. Therefore, a body experiencing any type of stress will, preferentially, use cholesterol to manufacture cortisol. Vitamin D is actually a hormone, not a vitamin, and it too, must be produced by cholesterol. When we are under stress, our cholesterol is used to produce cortisol, depleting the amount needed to produce vitamin D.

This is important to note because it gives us a glimpse into how stress, cortisol, inflammation, and lowered vitamin D levels can lead to obesity and obesity-linked metabolic diseases. You see, obesity is more than just “eating too much”. It is actually an immune response to fat cells that is fed by inflammation and lowered vitamin D levels.

When our bodies are stressed and produce cortisol, our bodies start to pack fat around our organs to protect them from the onslaught of stress chemicals. Our immune system then has the fat cells release macrophages into the adipose tissues to create defenses against cellular debris and pathogens in this dense area. This immune reaction stimulates inflammation to set in so that the macrophages will have the energy and conditions that it needs to attack.

When macrophages are set into action, lymphocytes and other immune cells also respond to the inflammation, which creates even more inflammation, which in turn attracts more lymphocytes, and so on. This chain reaction of inflammation-causing immune responses is what makes obesity so dangerous. To make the situation more confusing, young fat cells can release extra macrophages and immune cells can be transformed into fat cells and some fat cells into immune cells.

All of these cells are intimately connected and they all create and react to hormones in our bodies. Fat is actually thought of as part of the immune system. When too much fat is present, the immune system goes to work trying to protect and manage itself. By doing so, it produces a vast amount of inflammatory chemicals which interfere with the use of insulin. The inflammation spreads through your body, causing muscle to deteriorate. It also causes your body to become resistant to the hormones that normally regulate weight, mood, appetite, digestion, and more.

Vitamin D has been found to prevent severe inflammatory reactions that lead to destruction all over the body. It is this same inflammation that is associated with metabolic disease, which shows us that there is a clear link between metabolism and the immune system. This is why illnesses like influenza are seen more prevalent in the winter months. It’s not that the flu isn’t around all year, it’s that people aren’t out in the sun during the winter months and aren’t producing enough vitamin D to have a healthy immune system.

Vitamin D increases production of antimicrobial peptides and prevents the immune system from releasing too many inflammatory cells. When enough vitamin D is produced, our immune system works more efficiently and correctly. It activates T-cells to fight off infections, invaders, viruses, and pathogens. These cells cannot do their jobs if not activated by vitamin D, and so the immune system will use macrophages and other types of less effective immune cells instead. This overproduction of ineffective immune cells contributes to the constant state of inflammation that obese people experience.

Vitamin D levels can be easily checked by your doctor. In general, people need more and more vitamin D as they get closer to obese. Once the threshold is crossed over and vitamin D is no longer produced, inflammation and obesity can be very hard to combat.

About the Author: Phil Le Breton is owner at Wholesale Nutrition. He has a strong interest in helping people achieve greater brain and body health with vitamins and supplements, with an emphasis on vitamin C powder. Wholesale Nutrition has provided the world with the best vitamin C and wholesale vitamins since 1970. Visit to buy high-quality discount vitamins today!



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