Archive for the ‘Coenzyme Q10’ Category

Migraine Treatment with Vitamins and Supplements

Saturday, September 19th, 2015
Vitamins for Migraines

Looking for a natural way to prevent migraines? Check out these vitamins and supplements, scientifically proven to help with migraine management.

Migraines can put you out of commission for days. Sometimes, your prescription medication just doesn’t do the job or you really don’t like the idea of putting so many chemicals into your body. Preventing and treating migraines may take a little research and legwork, but I think we can all agree that taking the time to get your migraines under control is time well spent.

Migraine Headache Triggers

First, you should know your triggers. Keep a diary of what you eat, how much you sleep, your menstrual cycle (if you’re a woman), your sleep schedule, and your stress level. Do this for a couple of months to try and pinpoint what your triggers are. Some are very specific, like a sudden loud sound. The estrogen drop that happens just before a woman’s period is a very common trigger. Withdrawal from caffeine or chocolate can cause migraines. Acetaminophen gives some people migraines after the pain-killing effects wear off. You may have heard people say that Chinese food causes migraines because of the high monosodium glutamate (MSG) content. However, many Chinese food chains discontinued use of MSG decades ago. Check your food labels. MSG is a powerful neurotoxin that puts your brain into fight or flight response so that food seems to taste stronger and it also makes food addictive.

Do Vitamins and Supplements Really Work?

Once you know your triggers you can try to avoid them or at least schedule life around the possible migraine. Prevention is the next step. Take your vitamins. Certain vitamins are known to eradicate migraines when taken properly. Each of the ones we will discuss here have had placebo-controlled trials that have shown that they actually do work for many people and have a reason behind why they specifically work for migraines.

Magnesium for Prevention

Magnesium plays many crucial roles in the body. Today, many people do not get adequate magnesium from foods because our soils have been depleted. In trials, almost all migraine suffers tested were low or deficient in magnesium. Magnesium seems to drop dramatically with estrogen, either causing menstrual migraines or making them worse. Supplementation for 2-5 months has been proven effective at preventing menstrual migraines. Supplementing daily is the only way to get a benefit, so keep track of your magnesium levels with your doctor if you want to go this route.

Coenzyme Q10 (CoQ10)

CoQ10 is an antioxidant supplement, but is also plays a part in your body’s generation of adenosine triphosphate (ATP). ATP is the source of energy for all of your cells and is a necessary component of muscle contraction. Because cholesterol reducing statin drugs block the synthesis of CoQ10, many people have problems with coordination, balance, energy, and muscle strength while taking them. If you take statin drugs, talk with your doctor. You can still supplement with CoQ10, but you will need much less because your body won’t process very much at a time.

In trials, CoQ10 has shown to be around 55% effective in preventing migraines. It starts working after about a month and has the most benefit after about 3 months of supplementation. Because of its very low incidence of side effects, this is one of the supplements being studied as a safe form of migraine prevention in children.

Vitamin B2 (Riboflavin)

Vitamin B2 is much like CoQ10. It aids in the synthesis of ATP for cellular energy and is an antioxidant, so it rids the body of inflammatory and toxic chemicals that could be contributing to your migraines. Vitamin B2 may also aid in the absorption of iron, which is needed to carry oxygen to cells. Low iron levels generally reveal low B vitamin levels as well. Trials show a 50% reduction in migraine occurrence and duration for those taking 400mg/day for 3 months. Side effects are very low, less than 1%, and are limited to diarrhea and increased urine production. Because B vitamins all work together, for example, B2 is synthesized into B6 in the body, it is important to keep vitamin B levels balanced. This is why vitamin B supplements are often sold as a “complex” or balanced dosage of each B vitamin. Have your doctor check your vitamin B levels and monitor which ones need to come up and note how this affects your migraines.


About the Author: Stacy A. Pessoney is Wholesale Nutrition’s Chief Editor and Communications Research Director. She has a strong interest in helping people achieve greater brain and body health with the help of vitamins and supplements, with an emphasis on vitamin C powder in the form of buffered vitamin C. Wholesale Nutrition has provided the world with the best vitamin C and wholesale vitamins since 1970. Visit to buy high-quality discount vitamins today!


This entire article may be reprinted free of charge provided that the “About the Author” section of the article, sources, and all links in the article are included. For shorter quotations, a clear link to the blog post or Wholesale Nutrition is sufficient.

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Alternative Treatments for Parkinson’s Disease

Wednesday, October 15th, 2014
Alternative Treatments for Parkinson’s Disease

Protect brain cells and relieve symptoms of Parkinson's Disease with Vitamin C and other Supplements.

Parkinson’s disease is a neurological disorder that affects movement of the body. It is a progressive disorder, worsening over time. It can have a very gradual development, starting with only a mild tremor, a lack of facial expression, stiff/painful muscles, or mild speech problems. There is no cure for Parkinson’s disease, but medications, vitamins and supplements can have a big effect on symptoms.

The Truth about CoQ10 Supplements

Tuesday, April 1st, 2014
CoQ10 is not recommended for many medical conditions.

CoQ10 is not recommended for many medical conditions. Check with your doctor and educate yourself on actual CoQ10 studies before you supplement.

Coenzyme Q10 (CoQ10) is an antioxidant made by the human body. CoQ10 is needed for cells to function and to convert food into energy. CoQ10 levels decrease as we age. The lowest CoQ10 levels are found in people with diabetes, cancer, HIV/AIDS, muscular dystrophies, Parkinson’s disease, genetic disorders, and heart conditions.

Alcohol Related Vitamin Deficiency and Hangovers

Thursday, July 28th, 2011

When alcohol is broken down by the liver, it is converted to acetaldehyde, which is between 10 and 30 times more toxic than the alcohol that was consumed. As this happens, other enzymatic systems in the body are inhibited and the liver must focus its energy on repairing these systems. Therefore, it is unable to perform its duties of helping blood glucose levels rise back up to acceptable levels. Alcohol consumption also keeps the kidneys from inhibiting diuresis, which means the body becomes dehydrated.

The brain needs high levels of glucose and water to function, so the combined dehydration and hypoglycemia cause extreme fatigue, fogginess, headaches, light sensitivity, depth perception, depression, anxiety, and more. Additionally, the over-production of urine and dehydration cause many vitamins and nutrients to be flushed from the body.

Normally, the liver would be able to remove toxins, such as acetaldehyde, from the body. However, because the liver’s supply of peptides and amino acids, such as glutathione, are flushed, it is unable to remove dangerous toxins and free radicals. Furthermore, the presence of ethanol in the body causes the enzyme cytochrome P450 2E1 (CYP2E1) to be activated. This enzyme produces a flood of toxins and free radicals in the body, which the liver is unable to handle. This enzyme also interferes with the way most medications work, putting you at an even higher risk for disease.

When ethanol is present in the bloodstream, metabolism is suppressed, causing many of these enzymatic processes to be slowed. This is why a hangover is not usually felt until the alcohol has “worn off”. It is also why many hangover symptoms can be “cured” by drinking more alcohol. This is a very dangerous way to cure a hangover because you are stacking toxins on top of toxins and further inhibiting, and likely permanently squelching, your body’s ability to recover.

Antioxidant vitamins and supplements can help you to aid your liver in removing damaging free radicals. Vitamins must be replaced to get the body back in balance so that it can function normally. Vitamins are not just for making you feel better, but are necessary for you to protect yourself from disease caused by the havoc that alcohol wreaks on your body. Thiamine, vitamin B1, is the most common deficiency found in people that consume alcohol. This deficiency causes irreversible brain damage, inhibits the absorption of vitamins and nutrients, and when left untreated, causes damage to the liver, intestines, and pancreas.

Vitamins are necessary for helping your body recover from alcohol use. Vitamin C is an excellent choice of antioxidant if you’re looking to protect your cells from damage and remove toxins from the body. When combined with other antioxidants, like vitamin E and CoQ10, the protective qualities are enhanced and prolonged. The best vitamin C is a buffered vitamin c powder, a non-acidic, highly absorbable form of vitamin C is a good way to get started on a vitamins and supplements routine. Have your vitamin B levels checked by your physician so that they can help you decide which daily vitamins are right for you.

Properly taking care of your body before and after alcohol consumption will help your body to absorb the vitamins that you take, store the ones that need to be stored, and use them in the way that they are supposed to be used.

About the Author: Phil Le Breton is owner at Wholesale Nutrition. He has a strong interest in helping people achieve greater brain and body health with vitamins and supplements, with an emphasis on vitamin C powder. Wholesale Nutrition has provided the world with the best vitamin C and wholesale vitamins since 1970. Visit to buy high-quality discount vitamins today!



This entire article may be reprinted free of charge provided that the “About the Author” section of the article, sources, and all links in the article are included. For shorter quotations, a clear link to the blog post or Wholesale Nutrition is sufficient.

Cholesterol and You: The Good (HDL), the Bad (LDL) and the Ugly (Plaque) Part 3

Wednesday, July 29th, 2009

Part 3: Lowering Cholesterol Naturally

Vitamin C can help regulate cholesterol synthesis in the liver. This means that by keeping your vitamin C levels up, your body can more efficiently carry LDL (bad cholesterol) from the arteries to the liver for processing. This can greatly reduce your blood cholesterol levels without changing the chemistry of your body.

We talked about how statins lowered cholesterol by replacing the enzyme HMG-CoA reductase in part 2 of this series. This replacement, which causes the production of the protein that causes LDL to increase, is also what contributes to the depletion of CoQ10. Vitamin C reduces the action of the enzyme HMG-CoA, but does not replace it. It does not cause the chemical chain reaction that depletes the body of necessary enzymes, such as CoQ10. In fact, adequate vitamin C levels promote the natural production of CoQ10 and other enzymes in the body.

Our veins and arteries need vitamin C and CoQ10 to produce the collagen and elastin that they need to keep from breaking down. Inadequate production can lead to chronic instability of the vessel walls. As a result of this instability, deposits can develop over time and lead to cardiovascular disease. Furthermore, if we are deficient, then the body produces more and more cholesterol and plaque to strengthen the arterial walls.

But wait, there’s more! Vitamin C is also an antioxidant. As an added benefit, it helps prevent oxidation of cholesterol particles in the arteries. If we are vitamin C deficient, this cholesterol will harden (oxidize) and form plaque. If we take adequate amounts of vitamin C these cholesterol particles are carried out of the arteries rather than forming deposits via oxidation.

It is interesting to note that unlike most animals, we do not make our own vitamin C. In fact, most other animals (besides higher order primates) make hundreds of times more vitamin C daily than we get through our diet. There is evidence that suggests that this may be why heart disease in animals is virtually non-existent.

Many new studies have shown that supplementing with vitamin C, vitamin E and lysine can prevent plaque from building up in the heart and even remove plaque that has already built up. Vitamin C inhibits the LDL proteins from oxidizing, which causes platelets and fatty plaques to adhere to arterial walls.

Niacin helps to raise good cholesterol (HDL) and lower your LDL (bad cholesterol) levels. Niacin also helps vitamin C navigate through glucose, increasing its effectiveness. This makes niacin and vitamin C a powerful combination for lowering cholesterol in diabetics.

Additionally, fish oil supplementation has been shown to greatly reduce triglycerides. Triglycerides come from the fats that we eat, or they are produced by the body when we eat more carbohydrates than are necessary. Your body should store triglycerides for energy between meals. But, too many carbohydrates and too much fat can cause triglyceride levels to remain high and contribute to plaque build-up and heart disease.

Essential fatty acids, like Omega-3 fatty acids, specifically DHA and EPA, help to reduce triglyceride levels. You may see a slight increase in LDL levels if you are supplementing with fish oils, but don’t worry. The calculated value of LDL is more accurate once triglyceride levels are under control. Also, triglycerides are converted into LDL, and are less harmful in this form.

Soluble fiber also helps to lower LDL levels. Taken or obtained through diet daily, it can lower your LDL levels by as much as 20%. Soluble fiber slows down the digestive process (helping glucose levels also) and binds to LDL particles in the intestines, carrying them out of the body before they enter the bloodstream. And less LDL equates to less plaque and as a consequence, a healthier heart. The product “Eurofiber”, available exclusively at Wholesale Nutrition, contains the best forms of soluble fiber, combined with a high dose of vitamin C for lowering cholesterol.

Talk with your doctor before you start supplementing to lower your cholesterol, especially if you are taking statins or other medications. To get an adequate dosage of vitamin C, you may want to take vitamin C powder. If you have high cholesterol, it is important to continue treating it once you start and work closely with your physician.

About the Author: Phil Le Breton is owner at Wholesale Nutrition. He has a strong interest in helping people achieve greater brain and body health. For more information about C-Salts, otherwise known as the best Vitamin C, or about other Vitamin C powder products, visit where you can buy Vitamins and Supplements of the highest quality.

Coenzyme Q10: The Different Forms and Heart Health (Part 2)

Tuesday, July 7th, 2009

Part 2: Ubiquinol vs. Ubiquinone

If you have been looking into supplementing with coenzyme Q10, you may have run into the types “ubiquinol” and “ubiquinone”. Both types are very important nutrients to the human body. Understanding the differences in the two can help you be sure that you are maximizing the benefits you receive from supplementing with CoQ10.

CoQ10 is needed to help the organs with the highest energy requirements repair and protect themselves. As mentioned in Part 1 of this series, ubiquinol levels are greatly reduced in cancer and heart disease patients. Levels are also low in patients with neurological and liver conditions. It is believed that low levels of CoQ10 put the body at higher risk for these conditions and supplementing can help you protect yourself.

Ubiquinone is the most widely recognized form of CoQ10. It is a powerful antioxidant produced naturally in the body. It plays a key role in cellular energy production. The body converts ubiquinone into ubiquinol. This conversion is necessary for cellular use. The body combines fats and carbohydrates with oxygen inside the cells to produce energy. Ubiquinol, being fat-soluble, passes freely into and out of the cell. It cleans out free radicals and quickly transports the signal to produce energy from the cellular mitochondria.

So, the body needs ubiquinone to convert into the usable form, ubiquinol. The human body begins to lose ubiquinone in its early twenties. Conversion of ubiquinone into ubiquinol becomes inhibited with age and sharply diminishes after age 40. Without enough ubiquinone and/or ubiquinol, the body becomes susceptible to age related fatigue and does not have the cellular energy to defend against oxidative stress. It also loses its ability to create collagen and elastin without enough CoQ10. These are substances necessary for cellular repair.

Ubiquinone has been available for about thirty years. It is the most recognizable form of CoQ10 because ubiquinol has only been available in supplement form since 2006. Both are equally important, but ubiquinol oxidizes rapidly outside of the body. Therefore, it took many years of research before it was available in supplement form.

Ask your doctor if CoQ10 supplementation is right for you. In general, ubiquinone supplementation may be necessary after age 20, while ubiquinol may not be necessary until after age 40 when the ability to convert ubiquinone diminishes.

Staying healthy and combating oxidative stress is not always possible without the use of vitamins and supplements. Remember from Part 1 of this series, that CoQ10 is most efficient when combined with vitamin C. Vitamin C promotes the production of CoQ10 in the body. Unfortunately for us, human beings do not produce vitamin C and it is necessary for us to get it from food sources and supplementation. Vitamin C powder is the easiest way to get enough vitamin C to be beneficial.

With the right combination of vitamin C, ubiquinol and ubiquinone, you can possibly prevent and repair damage to organs, ward off disease and increase your energy. Be proactive about your health and remember to talk to your doctor about supplementation before you begin any new regimen.

About the Author: Phil Le Breton is owner at Wholesale Nutrition. He has a strong interest in helping people achieve greater brain and body health. For more information about C-Salts, otherwise known as the best Vitamin C, or about other Vitamin C powder products, visit where you can buy Vitamins and Supplements of the highest quality.

Coenzyme Q10: The Different Forms and Heart Health (Part 1)

Monday, July 6th, 2009

Part 1: Have a Healthy Heart

We are becoming more aware of how important it is to protect our heart health. With nearly 13 million Americans currently affected by coronary heart disease, it is the number one killer of men and women in the United States, today. Statistics show that someone in the U.S. has a heart attack about every twenty seconds. Being proactive about your heart health can save your life.

There are a number of American lifestyle choices that can lead to an inevitable heart attack or heart disease. Just because it is slow to develop and easy to ignore does not mean that it isn’t happening to you. Lack of regular exercise, being overweight, eating a high fat diet, and smoking, all put you at a high risk for heart disease. We, as a nation, rely heavily on the “fix me” attitude instead of focusing on prevention.

You can help protect your heart from damage using Vitamins and Supplements that target heart health. Coenzyme Q10 (CoQ10 or Ubiquinone) is a compound made naturally in the human body, but the amount produced sharply reduces as we age, leaving our hearts at risk from as early as 21 years old. CoQ10 protects cells from environmental contaminants and disease. The damage that occurs can lead to heart attack, heart disease and even cancer.

If you are undergoing cancer treatment, be sure to ask your doctor about taking any supplements, like CoQ10, because they can interact with some cancer therapies. Your doctor may tell you to take it because it protects the heart from damage caused by many cancer medications. As an additional note, CoQ10 can slightly lower blood sugar levels and is not recommended for diabetic patients, unless monitored by a physician.

CoQ10 helps heart cells resist infection by boosting the immune system and neutralizing free radicals. Free radicals can damage DNA and mitochondria (responsible for cellular energy), hindering the response time needed by cells to keep a heart healthy. It speeds up the rate in which chemical reactions take place in cells, thus keeping the heart’s defenses in top shape. The cells of the heart have the highest energy requirements of all human organs and thus, naturally contain more of this coenzyme than any other cells. As we age, our cells are depleted of this necessary nutrient.

CoQ10 and vitamin C powder (ascorbic acid) are two of the most important essential nutrients to human health. Both are actually needed to repair heart cells. Vitamin C and Ubiquinone provide the cellular reactions necessary to produce collagen and elastin, the structural proteins of the heart muscle. CoQ10 and ascorbic acid studies have shown that they can control detrimental changes in the body that occur with age. They were also found to reverse age related degradation of the heart and immune system.

If you think that supplementing your diet with vitamin C and CoQ10 could help protect your heart and body from heart disease, you could be right. However, you should always talk to your doctor about drug interactions and also about how each supplement could affect an existing health condition. Supplementation combined with a few lifestyle and diet adjustments could help you live a much longer, healthier life.

“Part 2” of the CoQ10 series will focus on the different forms of CoQ10.

About the Author: Phil Le Breton is owner at Wholesale Nutrition. He has a strong interest in helping people achieve greater brain and body health. For more information about C-Salts, otherwise known as the best Vitamin C, or about other Vitamin C powder products, visit where you can buy Vitamins and Supplements of the highest quality.